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2015|16 Annual Report Fraunhofer IGB - AMBULUNG – BIOARTIFICIAL LUNG

63 Contact Outlook The “AmbuLung” should one day serve as a temporary portable artificial lung for patients with chronic obstructive pulmonary disease. This will enable the patients to leave the hospital and regain more independence and mobility, which will significantly improve their health and their uality of life 1 Homogeneous peptide functionalization of the hollow fiber “AmbuLung” module (fluorescently labeled REDVGK peptides). 2 Upscaling to a stack of 66 mats in “AmbuLung”. 3 Formation of a complete endothelial monolayer on biofunctionalized polymethylpentene hollow fibers (blue: cell nuclei, red: cell-cell contacts). 4 Endothelium on biofunctionalized polymethyl- pentene hollow fibers after 7 or 14 days of culture. Funding The research pro ect mbulatory Bioartificial ung mbu ung has received funding from the European Union’s Seventh Frame- work Programme for research, technological development and demonstration under grant agreement no 304932. Project partners Novalung GmbH, Heilbronn, Germany | Imperial College of Sci- ence, Technology and Medicine, London, UK | Università degli Studi di Firenze, Italy Further information 3 4 Prof. Dr. rer. nat. Petra Kluger Phone +49 711 970-4072 Dr. rer. nat. Kirsten Borchers Phone +49 711 970-4121 34 Phone +49711970-4072 Phone +49711970-4121